SPRY2 Protein (Myc-DYKDDDDK Tag)
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- Target Alle SPRY2 Proteine anzeigen
- SPRY2 (Sprouty Homolog 2 (SPRY2))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses SPRY2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
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- Recombinant human Sprouty homolog 2 / SPRY2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SPRY2 Protein
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
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The tag is located at the C-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SPRY2 (Sprouty Homolog 2 (SPRY2))
- Andere Bezeichnung
- Sprouty Homolog 2,spry2 (SPRY2 Produkte)
- Synonyme
- wu:fk66h11 Protein, wu:fk93e11 Protein, zgc:110440 Protein, hspry2 Protein, xspry2 Protein, sprouty2 Protein, Xsprouty2 Protein, sprouty-2 Protein, Xtsprouty2 Protein, hSPRY2 Protein, sprouty RTK signaling antagonist 2 Protein, sprouty RTK signaling antagonist 2 S homeolog Protein, sprouty homolog 2 (Drosophila) Protein, spry2 Protein, SPRY2 Protein, spry2.S Protein, Spry2 Protein
- Hintergrund
- This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein.
- Molekulargewicht
- 34.5 kDa
- NCBI Accession
- NP_005833
- Pathways
- EGFR Signaling Pathway, Sensory Perception of Sound, EGFR Downregulation
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