SPOP-B Protein (Transcript Variant 6) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2732612

Produktdetails

Target: SPOP-B (Speckle-Type POZ Protein (SPOP-B))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 6

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SPOP-B Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human SPOP (transcript variant 6) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: SPOP-B (Speckle-Type POZ Protein (SPOP-B))

Andere Bezeichnung: Spop (SPOP-B Produkte)

Synonyme: BTBD32 Protein, TEF2 Protein, AI315626 Protein, Pcif1 Protein, zgc:64140 Protein, spop Protein, tef2 Protein, speckle type BTB/POZ protein Protein, speckle-type POZ protein Protein, speckle type POZ protein S homeolog Protein, SPOP Protein, Spop Protein, spop Protein, spop.S Protein

Hintergrund: This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein.

Molekulargewicht: 42 kDa

NCBI Accession: NP_001007230