SPDEF/PSE Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2732544

Produktdetails

Target: SPDEF/PSE (SPDEF) (Proximal Sequence Element 1 (SPDEF))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SPDEF/PSE Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human SPDEF protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: SPDEF/PSE (SPDEF) (Proximal Sequence Element 1 (SPDEF))

Andere Bezeichnung: Spdef (SPDEF Produkte)

Synonyme: PDEF Protein, RP11-375E1__A.3 Protein, bA375E1.3 Protein, pdef Protein, Pse Protein, SAM pointed domain containing ETS transcription factor Protein, SAM pointed domain containing ets transcription factor Protein, SPDEF Protein, Spdef Protein

Hintergrund: The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 37.3 kDa

NCBI Accession: NP_036523