SNX15 Protein (Transcript Variant A) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2732393

Produktdetails

Target: SNX15 (Sorting Nexin 15 (SNX15))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant A

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SNX15 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Sorting nexin-15 (SNX15) (transcript variant A) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: SNX15 (Sorting Nexin 15 (SNX15))

Andere Bezeichnung: Sorting Nexin-15 (Snx15) (SNX15 Produkte)

Synonyme: SNX15 Protein, hsaf001435 Protein, snx15 Protein, MGC154249 Protein, HSAF001435 Protein, 1500032B08Rik Protein, E130013C21Rik Protein, sorting nexin 15 Protein, sorting nexin 15 S homeolog Protein, SNX15 Protein, snx15.S Protein, snx15 Protein, Snx15 Protein

Hintergrund: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.

Molekulargewicht: 38.1 kDa

NCBI Accession: NP_037438