SLC19A3 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2732152

Produktdetails

Target: SLC19A3 (Slc19a3) (Solute Carrier Family 19, Member 3 (Slc19a3))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SLC19A3 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human SLC19A3 / THTR2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: SLC19A3 (Slc19a3) (Solute Carrier Family 19, Member 3 (Slc19a3))

Andere Bezeichnung: Slc19a3,thtr2 (Slc19a3 Produkte)

Synonyme: BBGD Protein, THMD2 Protein, THTR2 Protein, thtr2 Protein, MGC52872 Protein, MGC89434 Protein, si:dkey-223n17.4 Protein, slc19a3 Protein, A230084E24Rik Protein, AI788884 Protein, ThTr2 Protein, solute carrier family 19 member 3 Protein, solute carrier family 19 member 3 L homeolog Protein, solute carrier family 19 (thiamine transporter), member 3 Protein, thiamine transporter 2 Protein, solute carrier family 19 (thiamine transporter), member 3b Protein, solute carrier family 19, member 3 Protein, thiamine transporter 2-like Protein, SLC19A3 Protein, Slc19a3 Protein, slc19a3.L Protein, slc19a3 Protein, LOC486151 Protein, slc19a3b Protein, LOC100230080 Protein

Hintergrund: This gene encodes a ubiquitously expressed transmembrane thiamine transporter that lacks folate transport activity. Mutations in this gene cause biotin-responsive basal ganglia disease (BBGD) a recessive disorder manifested in childhood that progresses to chronic encephalopathy, dystonia, quadriparesis, and death if untreated. Patients with BBGD have bilateral necrosis in the head of the caudate nucleus and in the putamen. Administration of high doses of biotin in the early progression of the disorder eliminates pathological symptoms while delayed treatment results in residual paraparesis, mild mental retardation, or dystonia. Administration of thiamine is ineffective in the treatment of this disorder. Experiments have failed to show that this protein can transport biotin. Mutations in this gene also cause a Wernicke's-like encephalopathy.[provided by RefSeq, Jan 2010].

Molekulargewicht: 55.5 kDa

NCBI Accession: NP_079519

Pathways: Dicarboxylic Acid Transport