SIP1 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2732069

Produktdetails

Target: SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SIP1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human SIP1 / GEMIN2 (transcript variant alpha) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))

Andere Bezeichnung: Sip1,gemin2 (GEMIN2 Produkte)

Synonyme: SIP1 Protein, SIP1-delta Protein, 1700012N19Rik Protein, Sip1 Protein, sip1 Protein, sip1-delta Protein, wu:fc52a05 Protein, zgc:110274 Protein, gem nuclear organelle associated protein 2 Protein, gem (nuclear organelle) associated protein 2 Protein, gem nuclear organelle associated protein 2 S homeolog Protein, GEMIN2 Protein, Gemin2 Protein, gemin2.S Protein, gemin2 Protein

Hintergrund: This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.

Molekulargewicht: 31.4 kDa

NCBI Accession: NP_003607

Pathways: Ribonucleoprotein Complex Subunit Organization, Tube Formation