SH2B2 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2731946

Produktdetails

Target: SH2B2 (SH2B Adaptor Protein 2 (SH2B2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SH2B2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human SH2B2 / APS protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: SH2B2 (SH2B Adaptor Protein 2 (SH2B2))

Andere Bezeichnung: Sh2b2,aps (SH2B2 Produkte)

Synonyme: APS Protein, Aps Protein, SH2B adaptor protein 2 Protein, SH2B2 Protein, Sh2b2 Protein

Hintergrund: The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt&aposs lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway.

Molekulargewicht: 72.1 kDa

NCBI Accession: NP_066189

Pathways: Carbohydrate Homeostasis, Brown Fat Cell Differentiation