SETDB1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2731882

Produktdetails

Target: SETDB1 (SET Domain, Bifurcated 1 (SETDB1))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SETDB1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human SETDB1 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: SETDB1 (SET Domain, Bifurcated 1 (SETDB1))

Andere Bezeichnung: Setdb1 (SETDB1 Produkte)

Synonyme: ESET Protein, H3-K9-HMTase4 Protein, KG1T Protein, KMT1E Protein, TDRD21 Protein, AU022152 Protein, mKIAA0067 Protein, SETDB1 Protein, NV10069 Protein, fc07d03 Protein, si:ch211-81a5.6 Protein, wu:fc07d03 Protein, im:7143091 Protein, wu:fa04a12 Protein, wu:fj80h02 Protein, zgc:152899 Protein, SET domain bifurcated 1 Protein, SET domain, bifurcated 1 Protein, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 Protein, histone-lysine N-methyltransferase SETDB1 Protein, SET domain, bifurcated 1a Protein, SET domain bifurcated 1 L homeolog Protein, SET domain, bifurcated 1b Protein, SETDB1 Protein, Setdb1 Protein, MLLT11 Protein, LOC100120014 Protein, LOC100461671 Protein, setdb1a Protein, setdb1.L Protein, setdb1b Protein

Hintergrund: This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.[provided by RefSeq, Jun 2011].

Molekulargewicht: 142.8 kDa

NCBI Accession: NP_036564