BSCL2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2731605

Produktdetails

Target: BSCL2 (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses BSCL2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Seipin / BSCL2 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: BSCL2 (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2))

Andere Bezeichnung: Seipin,bscl2 (BSCL2 Produkte)

Synonyme: GNG3LG Protein, HMN5 Protein, SPG17 Protein, 2900097C17Rik Protein, AI046355 Protein, Gng3lg Protein, BSCL2, seipin lipid droplet biogenesis associated Protein, Berardinelli-Seip congenital lipodystrophy 2 (seipin) Protein, BSCL2 Protein, Bscl2 Protein

Hintergrund: This gene encodes the multi-pass transmembrane protein protein seipin. This protein localizes to the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U-like 2).[provided by RefSeq, Mar 2011].

Molekulargewicht: 44.2 kDa

NCBI Accession: NP_116056