RRM2B Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2731210

Produktdetails

Target: RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses RRM2B Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human RRM2B / P53R2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))

Andere Bezeichnung: Rrm2b,p53r2 (RRM2B Produkte)

Synonyme: p53r2 Protein, RRM2B Protein, MTDPS8A Protein, MTDPS8B Protein, P53R2 Protein, p53R2 Protein, ribonucleotide reductase M2 B (TP53 inducible) S homeolog Protein, ribonucleotide reductase regulatory TP53 inducible subunit M2B Protein, ribonucleotide reductase M2 B (TP53 inducible) Protein, rrm2b.S Protein, RRM2B Protein, rrm2b Protein, Rrm2b Protein

Hintergrund: This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]

Molekulargewicht: 40.6 kDa

NCBI Accession: NP_056528

Pathways: p53 Signalweg, Negative Regulation of intrinsic apoptotic Signaling