RORA Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2731073

Produktdetails

Target: RORA (RAR-Related Orphan Receptor A (RORA))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses RORA Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human ROR-alpha / RORA (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: RORA (RAR-Related Orphan Receptor A (RORA))

Andere Bezeichnung: Ror-Alpha,rora (RORA Produkte)

Synonyme: ror1 Protein, ror2 Protein, ror3 Protein, rzra Protein, nr1f1 Protein, MGC146531 Protein, NR1F1 Protein, ROR1 Protein, ROR2 Protein, ROR3 Protein, RZR-ALPHA Protein, RZRA Protein, RORalpha-B Protein, gb:dq017624 Protein, rora2 Protein, 9530021D13Rik Protein, Nr1f1 Protein, nmf267 Protein, sg Protein, staggerer Protein, tmgc26 Protein, RORalpha1 Protein, RAR related orphan receptor A Protein, RAR-related orphan receptor A Protein, RAR-related orphan receptor A, paralog a Protein, RAR-related orphan receptor alpha Protein, RORA Protein, rora Protein, Rora Protein, roraa Protein

Hintergrund: The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene.

Molekulargewicht: 58.8 kDa

NCBI Accession: NP_599023

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha