RNF213 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2731043

Produktdetails

Target: RNF213 (Ring Finger Protein 213 (RNF213))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses RNF213 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human RNF213 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: RNF213 (Ring Finger Protein 213 (RNF213))

Andere Bezeichnung: Rnf213 (RNF213 Produkte)

Synonyme: RNF213 Protein, ALO17 Protein, C17orf27 Protein, KIAA1618 Protein, MYMY2 Protein, MYSTR Protein, NET57 Protein, RGD1308168 Protein, 6030403J01 Protein, D11Ertd759e Protein, mKIAA1554 Protein, E3 ubiquitin-protein ligase RNF213 Protein, ring finger protein 213 Protein, LOC509283 Protein, LOC100626814 Protein, RNF213 Protein, LOC100461067 Protein, Rnf213 Protein

Hintergrund: This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(217)(p23q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(817)(q24q25) translocation has been identified with the MYC gene on chromosome 8. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 118.3 kDa

NCBI Accession: NP_066005