RNASEH2A Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2730998

Produktdetails

Target: RNASEH2A (Ribonuclease H2, Subunit A (RNASEH2A))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses RNASEH2A Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human RNASEH2A protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: RNASEH2A (Ribonuclease H2, Subunit A (RNASEH2A))

Andere Bezeichnung: Rnaseh2a (RNASEH2A Produkte)

Synonyme: 2400006P09Rik Protein, RNASEHI Protein, RNHIA Protein, RNHL Protein, zgc:56307 Protein, AGS4 Protein, JUNB Protein, ribonuclease H2 subunit A Protein, ribonuclease H2, large subunit Protein, ribonuclease H2, subunit A Protein, ribonuclease H2 subunit A L homeolog Protein, rnaseh2a Protein, RNASEH2A Protein, Rnaseh2a Protein, rnaseh2a.L Protein

Hintergrund: The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.[provided by RefSeq, Aug 2009].

Molekulargewicht: 33.2 kDa

NCBI Accession: NP_006388