RBPJ Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2730632

Produktdetails

Target: RBPJ (Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 3

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses RBPJ Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human RBP-J kappa / RBPJ (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: RBPJ (Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))

Andere Bezeichnung: Rbp-J Kappa,rbpj (RBPJ Produkte)

Synonyme: AOS3 Protein, CBF1 Protein, IGKJRB Protein, IGKJRB1 Protein, KBF2 Protein, RBP-J Protein, RBPJK Protein, RBPSUH Protein, SUH Protein, csl Protein, AI843960 Protein, Igkjrb Protein, Igkrsbp Protein, RBP-J kappa Protein, RBPjk Protein, Rbpsuh Protein, Su(H) Protein, XSu(H) Protein, xsu(h)1 Protein, Su(H)1 Protein, Su(h)A Protein, ik:tdsubc_1e8 Protein, rbpj Protein, rbpsuh Protein, xx:tdsubc_1e8 Protein, Su(H)2 Protein, su(h)B Protein, recombination signal binding protein for immunoglobulin kappa J region Protein, recombination signal binding protein for immunoglobulin kappa J region S homeolog Protein, recombination signal binding protein for immunoglobulin kappa J region a Protein, recombination signal binding protein for immunoglobulin kappa J region b Protein, RBPJ Protein, Rbpj Protein, rbpj.S Protein, rbpja Protein, rbpjb Protein

Hintergrund: The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9.

Molekulargewicht: 54 kDa

NCBI Accession: NP_976028

Pathways: Notch Signalweg, Stem Cell Maintenance, Smooth Muscle Cell Migration