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PRDM12 Protein (Myc-DYKDDDDK Tag)

PRDM12 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2729559
  • Target Alle PRDM12 Proteine anzeigen
    PRDM12 (PR Domain Containing 12 (PRDM12))
    Protein-Typ
    Recombinant
    Spezies
    • 1
    • 1
    Human
    Quelle
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses PRDM12 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human PRDM12 / PFM9 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PRDM12 Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PRDM12 (PR Domain Containing 12 (PRDM12))
    Andere Bezeichnung
    Prdm12,pfm9 (PRDM12 Produkte)
    Synonyme
    PRDM12 Protein, prdm12 Protein, MGC146714 Protein, PFM9 Protein, pfm9 Protein, Gm998 Protein, PR/SET domain 12 Protein, PR domain containing 12 Protein, PR domain containing 12 L homeolog Protein, PR domain containing 12a Protein, PRDM12 Protein, prdm12 Protein, prdm12.L Protein, Prdm12 Protein, prdm12a Protein
    Hintergrund
    This gene encodes a transcriptional regulator of sensory neuronal specification that plays a critical role in pain perception. The encoded protein contains an N-terminal PRDI-BF1 and RIZ homology (PR) domain, a SET domain, and three C-terminal C2H2 zinc finger DNA-binding domains. Naturally occurring mutations in this gene are associated with congenital insensitivity to pain (CIP), and hereditary sensory and autonomic neuropathies (HSAN&aposs) affecting peripheral sensory and autonomic neurons. Deregulation of this gene is associated with solid cancers and hematological malignancies including chronic myeloid leukaemia.
    Molekulargewicht
    40.2 kDa
    NCBI Accession
    NP_067632
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