PPP1R13B Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2729471

Produktdetails

Target: PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PPP1R13B Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human PPP1R13B protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))

Andere Bezeichnung: Ppp1r13b (PPP1R13B Produkte)

Synonyme: ASPP1 Protein, p53BP2-like Protein, p85 Protein, AI449786 Protein, AW545810 Protein, Tp53bp2 Protein, Trp53bp2 Protein, protein phosphatase 1 regulatory subunit 13B Protein, protein phosphatase 1, regulatory subunit 13B Protein, protein phosphatase 1 regulatory subunit 13B L homeolog Protein, protein phosphatase 1, regulatory subunit 13Bb Protein, protein phosphatase 1, regulatory (inhibitor) subunit 13B Protein, PPP1R13B Protein, Ppp1r13b Protein, ppp1r13b.L Protein, ppp1r13bb Protein, ppp1r13b Protein

Hintergrund: This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.

Molekulargewicht: 119.4 kDa

NCBI Accession: NP_056131

Pathways: p53 Signalweg