OCT4 Protein (His tag)
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- Target Alle OCT4 (POU5F1) Proteine anzeigen
- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses OCT4 Protein ist gelabelt mit His tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
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- Recombinant human POU class 5 homeobox 1 (POU5F1/OCT4), transcript variant 2, full length, with N-terminal HIS tag, expressed in E. coli, 50 μg (full length, N-term HIS tag, transcript variant 2) protein expressed in E.coli.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product POU5F1 Protein
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
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The tag is located at the N-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 50 μg/mL
- Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
- Andere Bezeichnung
- Pou Class 5 Homeobox 1 (Pou5f1/oct4) (POU5F1 Produkte)
- Synonyme
- OCT3 Protein, OCT4 Protein, OTF-3 Protein, OTF3 Protein, OTF4 Protein, Oct-3 Protein, Oct-4 Protein, POU5F1 Protein, gp9 Protein, gp-9 Protein, oct4 Protein, pou2 Protein, POU-2 Protein, cb197 Protein, spg/pou2 Protein, chunp6868 Protein, wu:fd18d06 Protein, NF-A3 Protein, Oct-3/4 Protein, Oct3 Protein, Oct3/4 Protein, Oct4 Protein, Otf-3 Protein, Otf-4 Protein, Otf3 Protein, Otf3-rs7 Protein, Otf3g Protein, Otf4 Protein, POU class 5 homeobox 1 Protein, POU domain, class 5, transcription factor 3 Protein, POU domain, class 5, transcription factor 1 Protein, POU5F1 Protein, pou5f3 Protein, Pou5f1 Protein
- Hintergrund
- This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing&aposs sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
- Molekulargewicht
- 21.1 kDa
- NCBI Accession
- NP_976034
- Pathways
- Stem Cell Maintenance
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