PLAGL1 Protein (His tag)

Produktnummer ABIN2729110

Produktdetails

Target: PLAGL1 (Pleiomorphic Adenoma Gene-Like 1 (PLAGL1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses PLAGL1 Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human PLAGL1 (full length, N-term HIS tag, transcript variant 7) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the N-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 50 mM Tris, pH 8.0, 500 mM NaCl, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PLAGL1 (Pleiomorphic Adenoma Gene-Like 1 (PLAGL1))

Andere Bezeichnung: Plagl1 (PLAGL1 Produkte)

Synonyme: PLAGL1 Protein, LOT1 Protein, ZAC Protein, ZAC1 Protein, Lot1 Protein, Zac1 Protein, PLAG1 like zinc finger 1 Protein, uncharacterized LOC100350914 Protein, pleiomorphic adenoma gene-like 1 Protein, PLAGL1 Protein, LOC100350914 Protein, Plagl1 Protein

Hintergrund: This gene encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth. This gene is often deleted or methylated and silenced in cancer cells. In addition, overexpression of this gene during fetal development is thought to be the causal factor for transient neonatal diabetes mellitus (TNDM). Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding two different protein isoforms. The P1 downstream promoter of this gene is imprinted, with preferential expression from the paternal allele in many tissues.

Molekulargewicht: 44.5 kDa

NCBI Accession: NP_001074424