PGBD3 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2728781

Produktdetails

Target: PGBD3 (PiggyBac Transposable Element Derived 3 (PGBD3))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PGBD3 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human PGBD3 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PGBD3 (PiggyBac Transposable Element Derived 3 (PGBD3))

Andere Bezeichnung: Pgbd3 (PGBD3 Produkte)

Synonyme: PGBD3 Protein, piggyBac transposable element derived 3 Protein, ERCC excision repair 6, chromatin remodeling factor Protein, PGBD3 Protein, ERCC6 Protein

Hintergrund: This gene is a member of a small family of genes derived from piggyBac transposable elements. The encoded protein contains a zinc-ribbon domain characteristic of transposon-derived proteins and may function as a regulator of transcription. Alternative splicing occurs between a splice site from exon 5 of the adjacent upstream gene &aposexcision repair cross-complementation group 6&apos (ERCC6, GeneID: 2074) and the 3&apos splice site upstream of the open reading frame (ORF) of this gene, which activates the alternative polyadenylation site downstream of the piggyback-derived-3 ORF. The resulting transcripts encode a fusion protein that shares sequence with the product of each individual gene. Pseudogenes for this gene are defined on chromosomes 4, 5 and 12.

Molekulargewicht: 67.4 kDa

NCBI Accession: NP_736609

Pathways: Chromatin Binding