PCDHGA12 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target Alle PCDHGA12 Proteine anzeigen
- PCDHGA12 (Protocadherin gamma 12 (PCDHGA12))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- Transcript Variant 1
- Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses PCDHGA12 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
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- Recombinant human PCDHGA12 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PCDHGA12 Protein
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
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The tag is located at the C-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PCDHGA12 (Protocadherin gamma 12 (PCDHGA12))
- Andere Bezeichnung
- Pcdhga12 (PCDHGA12 Produkte)
- Synonyme
- CDH21 Protein, FIB3 Protein, PCDH-GAMMA-A12 Protein, Pcdh13 Protein, pc2c Protein, protocadherin gamma subfamily A, 12 Protein, PCDHGA12 Protein, Pcdhga12 Protein
- Hintergrund
- This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
- Molekulargewicht
- 97.7 kDa
- NCBI Accession
- NP_003726
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