PADI2 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2728123

Produktdetails

Target: PADI2 (Peptidyl Arginine Deiminase, Type II (PADI2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PADI2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human PADI2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PADI2 (Peptidyl Arginine Deiminase, Type II (PADI2))

Andere Bezeichnung: Padi2 (PADI2 Produkte)

Synonyme: PADI2 Protein, PAD-H19 Protein, PAD2 Protein, PDI2 Protein, Pdi Protein, Pdi2 Protein, mKIAA0994 Protein, peptidyl arginine deiminase 2 Protein, peptidyl arginine deiminase, type II Protein, protein-arginine deiminase type-2 Protein, peptidyl arginine deiminase, type II S homeolog Protein, PADI2 Protein, padi2 Protein, LOC100357368 Protein, padi2.S Protein, Padi2 Protein

Hintergrund: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes.

Molekulargewicht: 75.4 kDa

NCBI Accession: NP_031391