P2RY12 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2728089

Produktdetails

Target: P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses P2RY12 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human P2RY12 / P2Y12 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))

Andere Bezeichnung: p2ry12,p2y12 (P2RY12 Produkte)

Synonyme: 2900079B22Rik Protein, 4921504D23Rik Protein, P2Y12 Protein, ADPG-R Protein, BDPLT8 Protein, HORK3 Protein, P2T(AC) Protein, P2Y(12)R Protein, P2Y(AC) Protein, P2Y(ADP) Protein, P2Y(cyc) Protein, SP1999 Protein, P2y12 Protein, purinergic receptor P2Y, G-protein coupled 12 Protein, purinergic receptor P2Y12 Protein, P2ry12 Protein, P2RY12 Protein

Hintergrund: The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene.

Molekulargewicht: 39.3 kDa

NCBI Accession: NP_073625