OCRL Protein (Transcript Variant B) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2727866

Produktdetails

Target: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant B

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses OCRL Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human OCRL (transcript variant b) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Andere Bezeichnung: Ocrl (OCRL Produkte)

Synonyme: OCRL Protein, wu:fi09g03 Protein, zgc:152864 Protein, locr Protein, nphl2 Protein, ocrl1 Protein, inpp5f Protein, INPP5F Protein, LOCR Protein, NPHL2 Protein, OCRL-1 Protein, OCRL1 Protein, 9530014D17Rik Protein, BB143339 Protein, OCRL, inositol polyphosphate-5-phosphatase Protein, phosphatidylinositol polyphosphate 5-phosphatase Protein, oculocerebrorenal syndrome of Lowe Protein, Ocrl Protein, NAEGRDRAFT_58601 Protein, OCRL Protein, ocrl Protein

Hintergrund: This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants.

Molekulargewicht: 103 kDa

NCBI Accession: NP_001578

Pathways: Inositol Metabolic Process