NOS1 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2727468

Produktdetails

Target: NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses NOS1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human NOS1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))

Andere Bezeichnung: Nos1 (NOS1 Produkte)

Synonyme: NOS1 Protein, IHPS1 Protein, N-NOS Protein, NC-NOS Protein, NOS Protein, bNOS Protein, nNOS Protein, 2310005C01Rik Protein, NO Protein, NOS-I Protein, Nos-1 Protein, nos Protein, ihps1 Protein, nnos Protein, nos1 Protein, nos1-A Protein, nanos C2HC-type zinc finger 1 Protein, nitric oxide synthase 1 Protein, nitric oxide synthase 1, neuronal Protein, nitric oxide synthase 1 (neuronal) Protein, nitric oxide synthase 1 L homeolog Protein, NANOS1 Protein, NOS1 Protein, Nos1 Protein, nos1 Protein, nos1.L Protein

Hintergrund: The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.[provided by RefSeq, Feb 2011].

Molekulargewicht: 160.8 kDa

NCBI Accession: NP_000611

Pathways: Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction