NRF2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2727219

Produktdetails

Target: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses NRF2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human NFE2L2 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Andere Bezeichnung: Nfe2l2 (NFE2L2 Produkte)

Synonyme: Nrf2 Protein, nfe2l2 Protein, wu:fc15g09 Protein, wu:fj67e03 Protein, NF-E2R2 Protein, NRF2 Protein, AI194320 Protein, nuclear factor, erythroid 2-like 2a Protein, nuclear factor, erythroid 2 like 2 S homeolog Protein, nuclear factor, erythroid 2 like 2 Protein, nuclear factor, erythroid derived 2, like 2 Protein, nuclear factor, erythroid 2-like 2 Protein, nfe2l2a Protein, nfe2l2.S Protein, NFE2L2 Protein, Nfe2l2 Protein

Hintergrund: This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene.

Molekulargewicht: 67.6 kDa

NCBI Accession: NP_006155

Pathways: ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling