MAL Protein (Transcript Variant B) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2725236

Produktdetails

Target: MAL (Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant B

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses MAL Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human MAL (transcript variant b) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: MAL (Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL))

Andere Bezeichnung: Mal (MAL Produkte)

Synonyme: AI326936 Protein, Bp50 Protein, GP39 Protein, HIGM1 Protein, IGM Protein, IMD3 Protein, T-BAM Protein, TRAP Protein, Tnfrsf5 Protein, p50 Protein, Mpv17 Protein, Vip17 Protein, mal Protein, wyatt Protein, MALGENE Protein, im:7142606 Protein, zgc:112003 Protein, mal, T-cell differentiation protein Protein, CD40 antigen Protein, myelin and lymphocyte protein, T cell differentiation protein Protein, myelin and lymphocyte protein Protein, toll-interleukin 1 receptor (TIR) domain containing adaptor protein L homeolog Protein, MAL Protein, Cd40 Protein, Mal Protein, LOC100135389 Protein, mal Protein, tirap.L Protein

Hintergrund: The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3.

Molekulargewicht: 11.9 kDa

NCBI Accession: NP_071883

Pathways: Asymmetric Protein Localization