HLA-DQB2 Protein (Myc-DYKDDDDK Tag)
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- Target Alle HLA-DQB2 Proteine anzeigen
- HLA-DQB2 (Major Histocompatibility Complex, Class II, DQ beta 2 (HLA-DQB2))
- Protein-Typ
- Recombinant
- Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses HLA-DQB2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
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- Recombinant human Major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product HLA-DQB2 Protein
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
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The tag is located at the C-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- HLA-DQB2 (Major Histocompatibility Complex, Class II, DQ beta 2 (HLA-DQB2))
- Abstract
- HLA-DQB2 Produkte
- Synonyme
- HLA-DQB1 Protein, HLA-DXB Protein, major histocompatibility complex, class II, DQ beta 2 Protein, HLA-DQB2 Protein
- Hintergrund
- HLA-DQB2 belongs to the family of HLA class II beta chain paralogs. Class II molecules are heterodimers consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. They play a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). Polymorphisms in the alpha and beta chains specify the peptide binding specificity, and typing for these polymorphisms is routinely done for bone marrow transplantation. However this gene, HLA-DQB2, is not routinely typed, as it is not thought to have an effect on transplantation. There is conflicting evidence in the literature and public sequence databases for the protein-coding capacity of HLA-DQB2. Because there is evidence of transcription and an intact ORF, HLA-DQB2 is represented in Entrez Gene and in RefSeq as a protein-coding locus.
- Molekulargewicht
- 27
- NCBI Accession
- NP_872355
- Pathways
- T-Zell Rezeptor Signalweg
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