Lipase A Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2724769

Produktdetails

Target: Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Lipase A Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human LIPA (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))

Andere Bezeichnung: Lipa (LIPA Produkte)

Synonyme: cesd Protein, lal Protein, LIPA Protein, CESD Protein, LAL Protein, Chole Protein, Chole2 Protein, Lip1 Protein, AA960673 Protein, Lal Protein, Lip-1 Protein, lipase A, lysosomal acid type Protein, lipase A, lysosomal acid, cholesterol esterase Protein, lipase A, lysosomal acid, cholesterol esterase L homeolog Protein, lysosomal acid lipase A Protein, LIPA Protein, lipa Protein, lipa.L Protein, Lipa Protein

Hintergrund: Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation. [UniProtKB/Swiss-Prot Function]

Molekulargewicht: 43 kDa

NCBI Accession: NP_000226