LIN28B Protein (His tag)

Produktnummer ABIN2724754

Produktdetails

Target: LIN28B (Lin-28 Homolog B (LIN28B))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses LIN28B Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human LIN28B (full length, N-term HIS tag) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the N-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 20 mM PB, pH 7.4.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: LIN28B (Lin-28 Homolog B (LIN28B))

Andere Bezeichnung: Lin28b (LIN28B Produkte)

Synonyme: csdd2 Protein, LIN-28 Protein, CSDD2 Protein, 2810403D23Rik Protein, D030047M17Rik Protein, Lin-28.2 Protein, lin-28 homolog B Protein, lin-28 homolog B S homeolog Protein, lin-28 homolog B (C. elegans) Protein, LIN28B Protein, lin28b Protein, lin28b.S Protein, Lin28b Protein

Hintergrund: The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3&apos UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation.

Molekulargewicht: 26.9 kDa

NCBI Accession: NP_001004317