KCNK4 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2724047

Produktdetails

Target: KCNK4 (Potassium Channel, Subfamily K, Member 4 (KCNK4))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses KCNK4 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human KCNK4 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: KCNK4 (Potassium Channel, Subfamily K, Member 4 (KCNK4))

Andere Bezeichnung: Kcnk4 (KCNK4 Produkte)

Synonyme: K2p4.1 Protein, TRAAK Protein, TRAAK1 Protein, MLZ-622 Protein, TRAAKt Protein, Tex40 Protein, KT4.1 Protein, potassium two pore domain channel subfamily K member 4 Protein, potassium channel, subfamily K, member 4 Protein, KCNK4 Protein, Kcnk4 Protein

Hintergrund: This gene encodes a member of the TWIK-related arachidonic acid-stimulated two pore potassium channel subfamily. The encoded protein homodimerizes and functions as an outwardly rectifying channel. This channel is regulated by polyunsaturated fatty acids, temperature and mechanical deformation of the lipid membrane. This protein is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia neurons. Alternate splicing results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream testis expressed 40 (TEX40) gene, as represented in GeneID: 106780802.

Molekulargewicht: 42.5 kDa

NCBI Accession: NP_201567