KCNAB1 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2724014

Produktdetails

Target: KCNAB1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 1 (KCNAB1))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 3

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses KCNAB1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human KCNAB1 (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: KCNAB1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 1 (KCNAB1))

Andere Bezeichnung: Kcnab1 (KCNAB1 Produkte)

Synonyme: KCNAB1 Protein, zgc:113627 Protein, AKR6A3 Protein, KCNA1B Protein, KV-BETA-1 Protein, Kvb1.3 Protein, hKvBeta3 Protein, hKvb3 Protein, Kvbeta1.1 Protein, KVBETA1 Protein, Kv-beta-1 Protein, Akr8a8 Protein, mKv(beta)1 Protein, KvBeta3 Protein, potassium voltage-gated channel subfamily A member regulatory beta subunit 1 Protein, potassium voltage-gated channel, shaker-related subfamily, beta member 1 a Protein, potassium voltage-gated channel, shaker-related subfamily, beta member 1 Protein, KCNAB1 Protein, kcnab1a Protein, Kcnab1 Protein

Hintergrund: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes distinct isoforms which are encoded by alternatively spliced transcript variants of this gene. Some of these isoforms are beta subunits, which form heteromultimeric complexes with alpha subunits and modulate the activity of the pore-forming alpha subunits.

Molekulargewicht: 44.5 kDa

NCBI Accession: NP_751891