KCNA2 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2724003

Produktdetails

Target: KCNA2 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 2 (KCNA2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses KCNA2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human KCNA2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: KCNA2 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 2 (KCNA2))

Andere Bezeichnung: Kcna2 (KCNA2 Produkte)

Synonyme: KCNA2 Protein, kcna2 Protein, HBK5 Protein, HK4 Protein, HUKIV Protein, KV1.2 Protein, MK2 Protein, NGK1 Protein, RBK2 Protein, Akr6a4 Protein, ENSMUSG00000074335 Protein, Gm10672 Protein, Kca1-2 Protein, Kv1.2 Protein, Mk-2 Protein, BK2 Protein, XSha2 Protein, k(v)1.2 Protein, kcna2-a Protein, kv1.2 Protein, potassium voltage-gated channel subfamily A member 2 Protein, potassium channel, voltage gated shaker related subfamily A, member 1 Protein, potassium voltage-gated channel, shaker-related subfamily, member 2 Protein, potassium channel, voltage gated shaker related subfamily A, member 2 S homeolog Protein, KCNA2 Protein, kcna1 Protein, Kcna2 Protein, LOC100537815 Protein, kcna2.S Protein

Hintergrund: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1.

Molekulargewicht: 56.5 kDa

NCBI Accession: NP_004965