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IL-33 Protein (Transcript Variant 1)

IL33 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 98 % , as determined by Coomassie stained SDS-PAGE. Func, AbP, STD, PI Active
Produktnummer ABIN2723710
  • Target Alle IL-33 (IL33) Proteine anzeigen
    IL-33 (IL33) (Interleukin 33 (IL33))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    Transcript Variant 1
    Spezies
    • 22
    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Quelle
    • 29
    • 8
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Applikation
    Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)
    Spezifität
    Optimal preservation of protein structure, post-translational modifications and functions.
    Produktmerkmale
    • Recombinant human Interleukin-33 (IL33) (transcript variant 1) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    Reinheit
    > 98 % , as determined by Coomassie stained SDS-PAGE.
    Endotoxin-Niveau
    Less than 0.01 ng per μg protein as determined by the LAL method.
    Biological Activity Comment
    The ED50 is 0.05 to 0.25 ng/ml, corresponding to a specific activity of 4 x 10^6 to 2 x 10^7 units/mg, determined by the dose dependent stimulation of anti-CD3 activated D10.G4.1 cell proliferation.
    Top Product
    Discover our top product IL33 Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    > 50 μg/mL
    Buffer
    1 x PBS
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    IL-33 (IL33) (Interleukin 33 (IL33))
    Andere Bezeichnung
    Interleukin-33 (Il33) (IL33 Produkte)
    Synonyme
    IL33 Protein, C9orf26 Protein, DVS27 Protein, IL1F11 Protein, NF-HEV Protein, NFEHEV Protein, RP11-575C20.2 Protein, 9230117N10Rik Protein, Il-33 Protein, Il1f11 Protein, RGD1311155 Protein, interleukin 33 Protein, IL33 Protein, Il33 Protein
    Hintergrund
    The protein encoded by this gene is a cytokine that binds to the IL1RL1/ST2 receptor. The encoded protein is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells. Several transcript variants encoding different isoforms have been found for this gene.
    Molekulargewicht
    18 kDa
    NCBI Accession
    NP_254274
    Pathways
    Production of Molecular Mediator of Immune Response
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