HYAL1 Protein (Transcript Variant 5) (His tag)

Produktnummer ABIN2723134

Produktdetails

Target: HYAL1 (Hyaluronidase-1 (HYAL1))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 5

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses HYAL1 Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human HYAL1 / Hyaluronidase-1 (transcript variant 5) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 95 % as determined by SDS-PAGE and Coomassie blue staining

Endotoxin-Niveau: Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Supplied as a 0.2 μM filtered solution of 20 mM TrisHCl, 150 mM NaCl, 10 % Glycerol, pH 7.5

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: HYAL1 (Hyaluronidase-1 (HYAL1))

Andere Bezeichnung: Hyal1,hyaluronidase-1 (HYAL1 Produkte)

Synonyme: HYAL-1 Protein, LUCA1 Protein, NAT6 Protein, Hya1 Protein, Hyal-1 Protein, hyaluronoglucosaminidase 1 Protein, HYAL1 Protein, Hyal1 Protein

Hintergrund: This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 47.18kD

NCBI Accession: NP_695017

Pathways: Glycosaminoglycan Metabolic Process