HSPB8 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2723117

Produktdetails

Target: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses HSPB8 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human HSPB8 / HSP22 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Andere Bezeichnung: Hspb8,hsp22 (HSPB8 Produkte)

Synonyme: CMT2L Protein, DHMN2 Protein, E2IG1 Protein, H11 Protein, HMN2 Protein, HMN2A Protein, HSP22 Protein, MGC64408 Protein, hsc70 Protein, wu:fb01g06 Protein, wu:fi48b06 Protein, fc09c11 Protein, wu:fc04b04 Protein, wu:fc09c11 Protein, zgc:64202 Protein, AU018630 Protein, AW413033 Protein, Cryac Protein, D5Ucla4 Protein, H11K Protein, HSP20-like Protein, Hsp22 Protein, heat shock protein family B (small) member 8 Protein, heat shock protein family B (small) member 8 L homeolog Protein, heat shock protein 8 Protein, heat shock protein b8 Protein, HSPB8 Protein, hspb8.L Protein, hspa8 Protein, hspb8 Protein, Hspb8 Protein

Hintergrund: The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

Molekulargewicht: 21.4 kDa

NCBI Accession: NP_055180