HEY2 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2722683

Produktdetails

Target: HEY2 (Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses HEY2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human HEY2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: HEY2 (Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))

Andere Bezeichnung: Hey2 (HEY2 Produkte)

Synonyme: CHF1 Protein, GRIDLOCK Protein, GRL Protein, HERP1 Protein, HESR2 Protein, HRT2 Protein, bHLHb32 Protein, Herp1 Protein, Hrt2 Protein, hesr2 Protein, grl Protein, zgc:136746 Protein, hes related family bHLH transcription factor with YRPW motif 2 Protein, hairy/enhancer-of-split related with YRPW motif 2 Protein, hes-related family bHLH transcription factor with YRPW motif 2 Protein, HEY2 Protein, Hey2 Protein, hey2 Protein

Hintergrund: This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.

Molekulargewicht: 35.6 kDa

NCBI Accession: NP_036391

Pathways: Regulation of Muscle Cell Differentiation