GLN1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2722012

Produktdetails

Target: GLN1 (Glutamine Synthetase (GLN1))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses GLN1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Glutamine synthetase (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: GLN1 (Glutamine Synthetase (GLN1))

Andere Bezeichnung: Glutamine Synthetase (GLN1 Produkte)

Synonyme: GLNS Protein, GS Protein, PIG43 Protein, PIG59 Protein, Glns Protein, glutamate-ammonia ligase Protein, glutamate-ammonia ligase (glutamine synthetase) Protein, glutamine synthetase Protein, GLUL Protein, Glul Protein, GLN1 Protein

Hintergrund: The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 41.9 kDa

NCBI Accession: NP_001028216

Pathways: Positive Regulation of Peptide Hormone Secretion