Gephyrin Protein (GPHN) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2721820

Produktdetails

Target: Gephyrin (GPHN)

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Gephyrin Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Gephyrin (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Gephyrin (GPHN)

Andere Bezeichnung: Gephyrin (GPHN Produkte)

Synonyme: 5730552E08Rik Protein, AI662856 Protein, BC027112 Protein, C230040D23 Protein, GPH Protein, GPHRYN Protein, geph Protein, Geph Protein, GPHN Protein, GEPH Protein, HKPX1 Protein, gpgb1 Protein, DKFZp459M0825 Protein, gephyrin Protein, gephyrin L homeolog Protein, gephyrin a Protein, Gphn Protein, GPHN Protein, gphn.L Protein, gphna Protein, PTRG_08978 Protein, VDBG_00775 Protein, Tsp_03043 Protein, gphn Protein

Hintergrund: This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described however, the full-length nature of all transcript variants is not currently known.

Molekulargewicht: 83.3 kDa

NCBI Accession: NP_065857

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development