GNA11 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2721492

Produktdetails

Target: GNA11 (Guanine Nucleotide Binding Protein (G Protein), alpha 11 (Gq Class) (GNA11))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses GNA11 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human G protein alpha 11 / GNA11 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: GNA11 (Guanine Nucleotide Binding Protein (G Protein), alpha 11 (Gq Class) (GNA11))

Andere Bezeichnung: G Protein alpha 11,gna11 (GNA11 Produkte)

Synonyme: Dsk7 Protein, E430025L19 Protein, GNA-11 Protein, HHC2 Protein, HYPOC2 Protein, G-alpha-11 Protein, gna11 Protein, si:dkey-42p8.2 Protein, wu:fb12d06 Protein, zgc:101761 Protein, guanine nucleotide binding protein, alpha 11 Protein, G protein subunit alpha 11 Protein, guanine nucleotide binding protein (G protein), alpha 11 (Gq class) Protein, guanine nucleotide regulatory protein G11 alpha subunit Protein, guanine nucleotide binding protein (G protein), alpha 11a (Gq class) Protein, guanine nucleotide binding protein (G protein), alpha 11 (Gq class) S homeolog Protein, guanine nucleotide binding protein (G protein), alpha 11b (Gq class) Protein, Gna11 Protein, GNA11 Protein, gna11 Protein, gna11a Protein, gna11.S Protein, gna11b Protein

Hintergrund: The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations.

Molekulargewicht: 41.9 kDa

NCBI Accession: NP_002058

Pathways: G-protein mediated Events