FREM1 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2721411

Produktdetails

Target: FREM1 (FRAS1 Related Extracellular Matrix 1 (FREM1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses FREM1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human FREM1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: FREM1 (FRAS1 Related Extracellular Matrix 1 (FREM1))

Andere Bezeichnung: Frem1 (FREM1 Produkte)

Synonyme: BNAR Protein, C9orf143 Protein, C9orf145 Protein, C9orf154 Protein, MOTA Protein, TILRR Protein, TRIGNO2 Protein, RGD1306981 Protein, BC037594 Protein, D430009N09 Protein, D630008K06 Protein, eye Protein, eyes2 Protein, heb Protein, qbrick Protein, FRAS1 related extracellular matrix 1 Protein, Fras1 related extracellular matrix 1 Protein, Fras1 related extracellular matrix protein 1 Protein, FREM1 Protein, Frem1 Protein

Hintergrund: This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation.

Molekulargewicht: 241.9 kDa

NCBI Accession: NP_659403