A2BP1 Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)
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- Target Alle A2BP1 Proteine anzeigen
- A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- Transcript Variant 4
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses A2BP1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
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- Recombinant human FOX1 / A2BP1 (transcript variant 4) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product A2BP1 Protein
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
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The tag is located at the C-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))
- Andere Bezeichnung
- Fox1,a2bp1 (A2BP1 Produkte)
- Synonyme
- A2BP1 Protein, fox1 Protein, a2bp1 Protein, zgc:103635 Protein, 2BP1 Protein, FOX-1 Protein, FOX1 Protein, HRNBP1 Protein, A2bp Protein, A2bp1 Protein, Hrnbp1 Protein, fox-1 Protein, RNA binding protein, fox-1 homolog 1 Protein, RNA binding fox-1 homolog 1 Protein, multicopper ferroxidase Protein, RNA binding protein, fox-1 homolog (C. elegans) 1 Protein, RBFOX1 Protein, rbfox1 Protein, FOX1 Protein, Rbfox1 Protein
- Hintergrund
- The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Molekulargewicht
- 42.6 kDa
- NCBI Accession
- NP_061193
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