FGF12 Protein (Transcript Variant 2) (His tag)

Produktnummer ABIN2721057

Produktdetails

Target: FGF12 (Fibroblast Growth Factor 12 (FGF12))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses FGF12 Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human FGF12 (transcript variant 2) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Reinheit: > 95 % as determined by SDS-PAGE and Coomassie blue staining

Endotoxin-Niveau: < 0.1 EU per μg protein as determined by LAL test

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, 5 mM EDTA, pH 7.5. Stable for at least 6 months from date of receipt under proper storage and handling conditions.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: FGF12 (Fibroblast Growth Factor 12 (FGF12))

Andere Bezeichnung: Fgf12 (FGF12 Produkte)

Synonyme: FHF1 Protein, FHF-1 Protein, MGC84150 Protein, FGF12 Protein, fgf12 Protein, zgc:153104 Protein, fhf1 Protein, fgf12b Protein, DKFZp459P139 Protein, FGF12B Protein, AV114868 Protein, FGF-12 Protein, Fhf1 Protein, Fhf1b Protein, fibroblast growth factor 12 Protein, fibroblast growth factor 12 S homeolog Protein, fibroblast growth factor 12a Protein, FGF12 Protein, fgf12.S Protein, fgf12a Protein, fgf12 Protein, Fgf12 Protein

Hintergrund: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.

Molekulargewicht: 20.5 kDa

NCBI Accession: NP_004104

Pathways: Negative Regulation of Transporter Activity