ESRRA Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2720550

Produktdetails

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses ESRRA Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Estrogen-related receptor alpha protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Andere Bezeichnung: Estrogen-Related Receptor alpha (ESRRA Produkte)

Synonyme: err1 Protein, erra Protein, esrral Protein, erralpha Protein, nr3b1 Protein, MGC80854 Protein, ESRRA Protein, esrl1 Protein, LOC100125507 Protein, ERRalpha Protein, Err1 Protein, Estrra Protein, Nr3b1 Protein, Errra Protein, ERR1 Protein, ERRa Protein, ESRL1 Protein, NR3B1 Protein, ESTRRA Protein, estrogen-related receptor alpha Protein, estrogen related receptor alpha L homeolog Protein, estrogen related receptor alpha Protein, catsper channel auxiliary subunit zeta Protein, estrogen related receptor, alpha Protein, esrra Protein, esrra.L Protein, ESRRA Protein, LOC100125507 Protein, CATSPERZ Protein, Esrra Protein

Hintergrund: The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1. Alternatively spliced transcript variants have been found for this gene.

Molekulargewicht: 45.3 kDa

NCBI Accession: NP_004442

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha