Estrogen Receptor alpha Protein (Transcript Variant 1) (His tag)

Produktnummer ABIN2720540

Produktdetails

Target: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Estrogen Receptor alpha Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Estrogen receptor alpha (transcript variant 1) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Reinheit: > 95 % as determined by SDS-PAGE and Coomassie blue staining

Endotoxin-Niveau: < 0.1 EU per μg protein as determined by LAL test

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, pH 7.2. Stable for at least 6 months from date of receipt under proper storage and handling conditions.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Andere Bezeichnung: Estrogen Receptor alpha (ESR1 Produkte)

Synonyme: LOC398734 Protein, AA420328 Protein, AU041214 Protein, ER-alpha Protein, ER[a] Protein, ERa Protein, ERalpha Protein, ESR Protein, Estr Protein, Estra Protein, Nr3a1 Protein, NR3A1 Protein, eralpha Protein, zfER[a] Protein, ER Protein, ESRA Protein, ESTRR Protein, Era Protein, akap12 Protein, cb27 Protein, esr1 Protein, fb72g12 Protein, id:ibd1202 Protein, sb:cb27 Protein, si:ch73-192g21.1 Protein, wu:fb72g12 Protein, wu:fc21c03 Protein, Esr Protein, RNESTROR Protein, ERALPHA Protein, er Protein, esr Protein, nr3a1 Protein, XER Protein, era Protein, esra Protein, ERbeta Protein, xesr-1 Protein, xlERalpha1 Protein, xlERalpha2 Protein, ESR1 Protein, estrogen receptor 1 L homeolog Protein, estrogen receptor 1 (alpha) Protein, estrogen receptor 1 Protein, A kinase (PRKA) anchor protein 12b Protein, esr1.L Protein, Esr1 Protein, ESR1 Protein, esr1 Protein, akap12b Protein

Hintergrund: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.

Molekulargewicht: 14.4 kDa

NCBI Accession: NP_000116

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly