EIF6 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2720114

Produktdetails

Target: EIF6 (Eukaryotic Translation Initiation Factor 6 (EIF6))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses EIF6 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human EIF6 / ITGB4BP (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: EIF6 (Eukaryotic Translation Initiation Factor 6 (EIF6))

Andere Bezeichnung: Eif6,itgb4bp (EIF6 Produkte)

Synonyme: CAB Protein, EIF3A Protein, ITGB4BP Protein, b(2)gcn Protein, eIF-6 Protein, p27(BBP) Protein, p27BBP Protein, 1110004P11 Protein, AA408895 Protein, Itgb4bp Protein, imc-415 Protein, MGC56562 Protein, itgb4bp4 Protein, zgc:56562 Protein, wu:fc28a04 Protein, wu:ft88f05 Protein, itgb4bp Protein, eukaryotic translation initiation factor 6 Protein, Eukaryotic translation initiation factor 6 Protein, eukaryotic translation initiation factor 6 S homeolog Protein, translation initiation factor eIF6 Protein, EIF6 Protein, Eif6 Protein, eif6 Protein, eif-6 Protein, eif6.S Protein, tif6 Protein

Hintergrund: Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene.

Molekulargewicht: 26.4 kDa

NCBI Accession: NP_852133

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly