DTX2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2719805

Produktdetails

Target: DTX2 (Deltex Homolog 2 (DTX2))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses DTX2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human DTX2 / RNF58 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: DTX2 (Deltex Homolog 2 (DTX2))

Andere Bezeichnung: Dtx2,rnf58 (DTX2 Produkte)

Synonyme: RNF58 Protein, 2610524D08Rik Protein, AA408415 Protein, AU022494 Protein, Deltex2 Protein, dtx2 Protein, deltex E3 ubiquitin ligase 2 Protein, probable E3 ubiquitin-protein ligase DTX2 Protein, deltex 2, E3 ubiquitin ligase Protein, deltex 2, E3 ubiquitin ligase S homeolog Protein, DTX2 Protein, Dtx2 Protein, LOC735784 Protein, LOC747633 Protein, dtx2 Protein, dtx2.S Protein

Hintergrund: Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. [UniProtKB/Swiss-Prot Function]

Molekulargewicht: 67.1 kDa

NCBI Accession: NP_065943

Pathways: Notch Signalweg