DCLK2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2719686

Produktdetails

Target: DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses DCLK2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Doublecortin-like kinase 2 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))

Andere Bezeichnung: Doublecortin-Like Kinase 2 (DCLK2 Produkte)

Synonyme: CL2 Protein, CLICK-II Protein, CLICK2 Protein, CLIK2 Protein, DCAMKL2 Protein, DCDC3 Protein, DCDC3B Protein, DCK2 Protein, 6330415M09Rik Protein, AU044875 Protein, Click-II Protein, Dcamkl2 Protein, DCLK2 Protein, cb572 Protein, dclk Protein, sb:cb572 Protein, si:dkey-180n16.1 Protein, Dck2 Protein, RGD1308384 Protein, doublecortin like kinase 2 Protein, doublecortin-like kinase 2 Protein, doublecortin-like kinase 2a Protein, DCLK2 Protein, Dclk2 Protein, dclk2a Protein

Hintergrund: This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants have been identified.

Molekulargewicht: 83.4 kDa

NCBI Accession: NP_001035350