DMAP1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2719531

Produktdetails

Target: DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses DMAP1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human DMAP1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

Andere Bezeichnung: Dmap1 (DMAP1 Produkte)

Synonyme: Afu4g07380 Protein, T8I13.5 Protein, DNMAP1 Protein, DNMTAP1 Protein, EAF2 Protein, MEAF2 Protein, SWC4 Protein, zgc:55593 Protein, dnmap1 Protein, dnmtap1 Protein, eaf2 Protein, meaf2 Protein, swc4 Protein, 1500016M21Rik Protein, Dmtap1 Protein, mKIAA1425 Protein, DNA methyltransferase 1-associated protein DMAP1 Protein, DNA methyltransferase 1-associated protein 1 Protein, DNA methyltransferase 1 associated protein 1 Protein, myb-like transcription factor family protein Protein, DNA methyltransferase 1 associated protein 1 L homeolog Protein, AFUA_4G07380 Protein, NFIA_108840 Protein, ACLA_046700 Protein, CpipJ_CPIJ017959 Protein, Bm1_47540 Protein, PMAA_026820 Protein, AFLA_112450 Protein, TSTA_072020 Protein, BDBG_02603 Protein, AT2G47210 Protein, CpipJ_CPIJ007438 Protein, DMAP1 Protein, dmap1 Protein, dmap1.L Protein, Dmap1 Protein

Hintergrund: This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.

Molekulargewicht: 52.8 kDa

NCBI Accession: NP_061973