PARK7/DJ1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2719515

Produktdetails

Target: PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PARK7/DJ1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human DJ-1 / PARK7 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))

Andere Bezeichnung: Dj-1,park7 (PARK7 Produkte)

Synonyme: DJ-1 Protein, DJ1 Protein, CAP1 Protein, Dj1 Protein, SP22 Protein, dj1 Protein, zgc:103725 Protein, park7b Protein, park7 Protein, park7a Protein, Parkinsonism associated deglycase Protein, Parkinson disease (autosomal recessive, early onset) 7 Protein, parkinson protein 7 Protein, parkinson protein 7 S homeolog Protein, parkinson protein 7 L homeolog Protein, PARK7 Protein, Park7 Protein, park7 Protein, park7.S Protein, park7.L Protein

Hintergrund: The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.

Molekulargewicht: 19.7 kDa

NCBI Accession: NP_009193

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport