Deoxyguanosine Kinase Protein (DGUOK) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2719393

Produktdetails

Target: Deoxyguanosine Kinase (DGUOK)

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Deoxyguanosine Kinase Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Deoxyguanosine kinase (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Deoxyguanosine Kinase (DGUOK)

Andere Bezeichnung: Deoxyguanosine Kinase (DGUOK Produkte)

Synonyme: DGUOK Protein, zgc:86625 Protein, dgk Protein, DDBDRAFT_0218264 Protein, DDBDRAFT_0233982 Protein, DDB_0218264 Protein, DDB_0233982 Protein, MTDPS3 Protein, dGK Protein, dGK1 Protein, dGK2 Protein, dGK3 Protein, deoxyguanosine kinase Protein, deoxyguanosine kinase L homeolog Protein, DGUOK Protein, dguok Protein, dguok.L Protein, dgk Protein, Ccan_04750 Protein, Dguok Protein

Hintergrund: In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.

Molekulargewicht: 27.9 kDa

NCBI Accession: NP_550438

Pathways: Ribonucleoside Biosynthetic Process